Production method of polypeptide
From:
NAMICROBIO CO.,LTD Date:08-02 377 Belong to:Industry Trends
Development history
With the development of science and technology, the methods of producing peptides are also developing. In the 1950s and 1960s, peptides were mainly obtained from animal organs. For example, the production method of thymosin is to kill the newborn calf, cut off its thymus, and then use the biotechnology of shock separation to shock and separate the peptide in the calf thymus to make thymosin injection. This thymosin is mainly used for human immunity. Nowadays, this peptide has been eliminated. Once popular in the world & ldquo; Mad cow disease;, The virus mainly devours proteins in animal brains and destroys brain tissues, cells and nerves. Once the human body is infected with this virus, it is more terrible than suffering from cancer, and finally becomes & ldquo; Vegetable & rdquo; Or die soon. On the verge of death or destruction, the peptides from human blood are also very effective. They are not only easy to cause hepatitis A, hepatitis B, hepatitis C, Ding Gan, HIV, venereal disease, but also have a different allergic reaction. Once this reaction occurs, life is at stake.
Synthesis method
Solid phase synthesis, liquid phase synthesis
A single peptide is synthesized from amino acids, which belongs to the intermediate of pharmaceutical raw materials. It is mainly used in the formulation of Western medicine to enhance the efficacy and enhance the absorption rate and absorption rate of human body
Acid hydrolysis or alkali hydrolysis
This peptide is mainly found in Japan. Produced by acid hydrolysis & ldquo; Soybean polypeptide & rdquo;, Genus & ldquo; Food Additives & rdquo;, It is mainly used for food for the elderly and children. Its purpose is to enhance the absorption of food nutrition by these two populations. The world has & ldquo; Soybean polypeptide & rdquo; The only countries in the world are Japan and China. However, the raw materials, hydrolysis methods and product properties are very different. The raw material used in Japan is soybean meal, and the hydrolysis method is acid method. The peptide produced is difficult to remove all acidic chemicals and has a bitter taste. It needs activated carbon to absorb and remove bitterness, and activated carbon will inevitably invade the peptide body
Bioactive peptides produced by enzymatic method
Bioactive peptides produced by enzymatic method. This peptide is mainly produced in China, which represents the level and trend of peptide research, development, production and innovation in the world. The bioactive peptide produced by enzymatic method uses the food grade plant protease needed by human body to enzymolysis the food protein eaten by human body into small molecular active peptides. It has biological activity and diversity. It has attracted attention all over the world and has become a hot spot in the world.
With the development of science and technology, the methods of producing peptides are also developing. In the 1950s and 1960s, peptides were mainly obtained from animal organs. For example, the production method of thymosin is to kill the newborn calf, cut off its thymus, and then use the biotechnology of shock separation to shock and separate the peptide in the calf thymus to make thymosin injection. This thymosin is mainly used for human immunity. Nowadays, this peptide has been eliminated. Once popular in the world & ldquo; Mad cow disease;, The virus mainly devours proteins in animal brains and destroys brain tissues, cells and nerves. Once the human body is infected with this virus, it is more terrible than suffering from cancer, and finally becomes & ldquo; Vegetable & rdquo; Or die soon. On the verge of death or destruction, the peptides from human blood are also very effective. They are not only easy to cause hepatitis A, hepatitis B, hepatitis C, Ding Gan, HIV, venereal disease, but also have a different allergic reaction. Once this reaction occurs, life is at stake.
Synthesis method
Solid phase synthesis, liquid phase synthesis
A single peptide is synthesized from amino acids, which belongs to the intermediate of pharmaceutical raw materials. It is mainly used in the formulation of Western medicine to enhance the efficacy and enhance the absorption rate and absorption rate of human body
Acid hydrolysis or alkali hydrolysis
This peptide is mainly found in Japan. Produced by acid hydrolysis & ldquo; Soybean polypeptide & rdquo;, Genus & ldquo; Food Additives & rdquo;, It is mainly used for food for the elderly and children. Its purpose is to enhance the absorption of food nutrition by these two populations. The world has & ldquo; Soybean polypeptide & rdquo; The only countries in the world are Japan and China. However, the raw materials, hydrolysis methods and product properties are very different. The raw material used in Japan is soybean meal, and the hydrolysis method is acid method. The peptide produced is difficult to remove all acidic chemicals and has a bitter taste. It needs activated carbon to absorb and remove bitterness, and activated carbon will inevitably invade the peptide body
Bioactive peptides produced by enzymatic method
Bioactive peptides produced by enzymatic method. This peptide is mainly produced in China, which represents the level and trend of peptide research, development, production and innovation in the world. The bioactive peptide produced by enzymatic method uses the food grade plant protease needed by human body to enzymolysis the food protein eaten by human body into small molecular active peptides. It has biological activity and diversity. It has attracted attention all over the world and has become a hot spot in the world.
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